Carolina Panthers quarterback Cam Newton was ruled out of the remainder of the NFL season on Tuesday after failing to overcome his long-term foot injury, the team said.
Newton, the former NFL MVP who led the Panthers to a Super Bowl berth in 2016, has not played this season since featuring in a defeat to Tampa Bay in week two.
The 30-year-old has been struggling to recover from a Lisfranc injury, a complicated condition which affects the bone structure of the foot.
In a statement on Tuesday, the Panthers said Newton was still experiencing pain despite following a program of rest and rehabilitation.
The quarterback has been placed on injured reserve, and will play no part in the remainder of the Panthers season.
"For the past seven weeks, Cam has diligently followed a program of rest and rehab and still is experiencing pain in his foot," general manager Marty Hurney said.
"He saw two foot specialists last week who agreed that he should continue that path prescribed by the team's medical staff, and that it likely will take significant time for the injury to fully heal.
"We have said all along that it is impossible to put a timetable on this injury. Nobody is more frustrated with that fact than Cam."
Before 2018 Newton had missed only three starts in seven years.
However he has been troubled by shoulder and foot issues since then which have impacted his form for the Panthers.
The Panthers are second in the NFC South with five wins and three defeats, but are lagging way behind leaders New Orleans, who are 7-1 through eight games.