The Who frontman will close out the cancer charity’s weeklong fundraising series on Sunday 26 March.
On Tuesday 21 March, the series will hold an evening of comedy featuring Alan Carr, Harry Hill, Russell Kane, Seann Walsh, Rosie Jones, Slim, Neil Delamere and Fatiha El-Ghorri.
In 2000, The Who kickstarted the concert series, which has raised millions of pounds for young people with cancer.
Last year’s 20th edition featured a once-in-a-lifetime acoustic show from The Who, as well as concerts by Ed Sheeran, Liam Gallagher, Yungblud, Madness and Don Broco.
Tickets for A Special Gala Evening of Music with Roger Daltrey and Friends of Teenage Cancer Trust, on 26 March, will go on sale on Friday 3 March at 9.30am GMT.
You can find additional line-up and ticketing information by visiting their website.
Teenage Cancer Trust at The Royal Albert Hall will take place between 20 and 26 March.