Fabio Quartararo claimed his fourth successive pole after dominating Italian MotoGP qualifying with what he hailed as "the best lap" of his career at Mugello on Saturday which he dedicated to Moto3 crash-victim Jason Dupasquier.
Dupasquier, 19, fell and was struck by another bike, before sliding along the track, in Moto3 qualifying.
Over half an hour after the incident he was still out on the circuit being attended to by medical officers.
The stricken teenager was then helicoptered to hospital in Florence.
"He was transferred to hospital in a hemodynamically stable way," the sport's medical officer Giancarlo di Filippo later reported.
He added: "We'll wait for further updates from the hospital."
Japanese rider Ayumu Sasaki and Spaniard Jeremy Alcoba were the others involved in the accident which delayed the MotoGP fourth practice with organisers reporting both were "fine".
Alcoba went to qualify sixth fastest for the race. Sasaki was 10th.
After sealing his pole Quartararo said: "I want to dedicate this one to Jason who had a really bad crash. I hope he's OK. I'm praying for him and I'm praying for his family."
Francesco Bagnaia had been fastest in all the first three practice sessions for local team Ducati, setting a new lap record in FP3 on Saturday morning.
Quartararo was top in final practice and kept the home favourites at bay again in qualifying.
The French Yamaha rider took pole in style, lowering the record Bagnaia set only hours earlier, with a new fastest time at the circuit of 1min 45.187sec.
Bagnaia, was second at 0.230sec, with Johann Zarco on Ducati satellite Pramac bike completing the front row of Sunday's grid.
"I enjoyed that lap," beamed Quartararo, 22.
"It's a track where you really feel the adrenaline and I was on the limit everywhere.
"I think its the best lap I ever did in my life."
Jack Miller, winner of the last two races, qualified in fifth and will be sandwiched between Aleix Espargaro (Ducati) and Brad Binder (KTM) on the second row.
South African Binder had earlier bettered the top speed ever in MotoGP, recorded by Johann Zarco in Qatar at the start of the season, when hitting 362.4kmh on his KTM in FP3.
Honda's multiple world champion Marc Marquez is still finding his way back to top form after returning from last season's injury and starts in 11th in this sixth leg of the championship.
Italian motorcycling legend Valentino Rossi's inauspicious 2021 continued with 'the doctor' down in 19th on Yamaha's SRT satellite bike.