Britain closed in Friday on a mid-February target to offer coronavirus vaccinations to 15 million of its most vulnerable people, raising hopes that a grinding lockdown could be eased.
Just over 14 million people have been given a jab since the world-first immunisation programme began in early December, with a daily average of 431,232 receiving a vaccine last week.
Prime Minister Boris Johnson has vowed to offer jabs to all top four priority demographics -- which includes over-70s, care home residents and some key workers -- by the end of this week.
"It looks like we are on target, we very much hope," Johnson said, hailing the efforts of medical staff and volunteers to keep the drive on track despite an icy cold snap in parts of Britain.
But about a million eligible people have still not come forward to take up appointments, he said, urging them to contact the state health service.
The devolved government in Wales, which controls its own health policy, said it had reached the target of vaccinating the top four categories on Friday.
Figures show nearly 22 percent of people in Wales have received at least a first jab, compared to 20.3 percent in England, 19.2 percent in Scotland and 18.7 percent in Northern Ireland.
"The race is to get as many people vaccinated as fast as we can so that we can begin to see this dreadful experience in the rear-view mirror," Welsh First Minister Mark Drakeford said.
The UK government in London, which is responsible for sourcing vaccines, is next aiming to have offered jabs to all over-50s by May and the entire adult population by September.
- 'Phased approach' -
Infection rates have dropped markedly across Britain over recent weeks, as strict lockdown measures have curbed previously spiralling case numbers, hospitalisations and deaths.
The Office for National Statistics' latest infection survey released Friday showed new cases decreasing in nearly every region of England, where it estimates around one in 80 people had the virus last week.
In early January it was as high as one in 50.
Meanwhile the virus's reproduction rate, the "R value", has fallen to between 0.7 and 0.9 -- the first time it has dropped below 1.0 since last July.
That means on average, every 10 people infected will infect between seven and nine others.
The improving situation has prompted calls from some of Johnson's Conservative MPs for stay-at-home rules to be lifted in early March, despite concern about the spread of virus variants that may be more resistant to vaccines.
A new 10-day hotel quarantine regime for British residents returning from 33 virus variant hotspots begins on Monday, despite criticism it is too late.
Johnson has vowed to review all relevant data next week, ahead of setting out the government's "roadmap" for the months ahead on February 22.
"We will set out a gradual and phased approach towards easing the restrictions in a sustainable way," his spokesman told reporters, noting it would include plans "for reopening schools and gradually reopening our economy and society".
But he added Britain remained "in a difficult situation" with its health service still under very significant pressure.
- 'In a better place' -
Epidemiologist Neil Ferguson, one of the government's most high-profile scientific advisers, said the country was now "in a better place than I might have anticipated a month ago".
Johnson will "have some bandwidth" to start reopening primary schools in early March before potentially easing other restrictions the following month, he said.
But Ferguson cautioned against moving too hastily.
"If we relax too quickly without seeing the effect of each stage of relaxation, we may do what we've done before and relax too much, see a surge in case numbers, and still need to tighten up measures again," he told a Politico podcast.