STORY: The sailing was made possible after Turkey and the United Nations brokered a grain-and-fertilizer export agreement between Russia and Ukraine last month.
"The first grain ship since #RussianAggression has left port. Thanks to the support of all our partner countries & @UN we were able to full implement the Agreement signed in Istanbul," Ukrainian Infrastructure Minister Oleksandr Kubrakov said on Twitter.
The Turkish defense minister said earlier that the Sierra Leone-flagged ship Razoni, which is loaded with corn, will head to Lebanon. More ships will follow, it said.
Russia and Ukraine account for nearly a third of global wheat exports. But Western sanctions on Russia and fighting along Ukraine's eastern seaboard have prevented grain ships safely leaving ports.
The deal aims to allow safe passage for grain shipments in and out of Chornomorsk, Odesa and the port of Pivdennyi.