Sheeran's tour dates were revealed alongside details of his new album Subtract, which is due to be released in May.
Here is everything you need to know about the gigs.
Ed Sheeran UK and Ireland tour dates
Sheeran will perform at the following venues in the UK and Ireland next month:
23 March – Manchester, AO Arena
24 March – London, The O2
25 March – London, The O2
28 March – Glasgow, Hydro Arena
30 March – Dublin, 3Arena
It will be his first UK tour since last summer, when he performed at stadiums across the country.
The Shape of You musician, who has 13 UK number-one singles, is expected to play a mix of new material and his biggest hits.
Irish singer-songwriter Cian Ducrot has been announced as the support act.
How to buy tickets for the tour
Release date for Ed Sheeran's new album
The singer's new album Subtract will be released on 5 May, with lead single Eyes Closed due out on 24 March.
The 14-track, acoustic-driven record was made in collaboration with The National's Aaron Dessner.
The lyrics were written when Sheeran was "spiralling through fear, depression and anxiety" after his wife was diagnosed with a tumour and his close friend Jamal Edwards died.
In a statement, Sheeran said: "I felt like I was drowning, head below the surface, looking up but not being able to break through for air...
"For the first time I'm not trying to craft an album people will like, I'm merely putting something out that's honest and true to where I am in my adult life."
Subtract is the latest instalment in Sheeran's mathematical symbol series, which has progressed through albums including Equals and Divide.
The full album tracklist is:
Life Goes On
End of Youth
The Hills of Aberfeldy
The deluxe edition contains the following tracks:
Watch: Ed Sheeran reveals wife Cherry Seaborn was diagnosed with tumour