The reigning champions go into the encounter leading the way in Group D after kicking off their title defence with an emphatic 4-1 thrashing of Australia.
Yet Denmark, who began with a goalless draw against Tunisia, are bidding for a hat-trick of wins over Les Bleus, having already beaten them home and away this year.
“They are underestimated as a team,” Deschamps said.
“We are talking about a four-month period where they beat us twice and made life very difficult for us. We will have to make sure that’s not the case (this weekend).
“It is not a question of revenge because we know the Danish players and they know us. They can change system from one match to the other and that can give us different types of difficulties.”
Deschamps will be forced into at least one change to the starting XI which began against Australia as Bayern Munich defender Lucas Hernandez is out of the rest of the tournament with an anterior cruciate ligament injury.
Denmark won 2-1 in Paris in June before defeating the world champions 2-0 in Copenhagen at the end of September.
France captain Hugo Lloris said those setbacks serve as a warning but insisted his team do not need additional incentives as they seek to book a spot in the knockout stages.
“It gives you an idea of the level of this Danish team,” the Tottenham goalkeeper said of the losses.
— French Team ⭐⭐ (@FrenchTeam) November 25, 2022
“It’s a wake-up for us. We don’t need any extra motivation. We are fully aware of the importance.
“We know it will be a decisive game for qualification. Every team is in a good place physically and athletically. We know it will be a big challenge – and we have to be ready.”
Denmark midfielder Thomas Delaney will miss the remainder of the competition with a knee injury sustained in the stalemate with Tunisia.