Biogen, Inc. BIIB announced that it has exercised its option with private biotech, TMS Co., Ltd. to acquire the latter’s phase II acute ischemic stroke candidate TMS-007. We remind investors that Biogen had signed the option deal with TMS in June last year.
The decision to acquire TMS-007 was based on positive data from a phase IIa study. The study met its primary endpoint and demonstrated TMS-007’s positive impacts on blood vessel reopening and patient functional recovery with no incidence of symptomatic intracranial hemorrhage (sICH).
sICH is a major complication of thrombolytic agent, which is presently approved for treating acute ischemic stroke caused by a blockage of blood supply to the brain. The use of thrombolytics for treating acute ischemic stroke is limited due to the increased risks of bleeding. There is significant unmet medical need for new therapies that can both improve clinical outcomes as well as extend the time after stroke onset so that a patient can be given thrombolytic treatment. TMS-007 is designed to restore blood flow following acute stroke and has shown the potential to provide an extended treatment window compared to currently approved thrombolytic agents.
For acquiring TMS-007, Biogen will make a one-time payment of $18 million to TMS with up to $335 million payable as potential milestone payments. Going forward, Biogen will be responsible for the development and commercialization of TMS-007.
With this acquisition, Biogen aims to boost its acute neurology portfolio, a strategic move for the company’s growth. Biogen is trying to diversify its pipeline and aims to be a leader in neuroscience and the adjacent therapeutic area. In almost four years from 2017-2020, Biogen executed 20 business development transactions, which significantly boosted its pipeline.
Among some recent deals, Biogen signed a collaboration with Sangamo Therapeutics SGMO in 2020 to make gene regulation therapies for a range of neurological indications including Alzheimer's disease. It also collaborated with Denali Therapeutics DNLI in August 2020 to co-develop and co-commercialize the latter’s small molecule LRRK2 inhibitor program, DNL151, for Parkinson’s disease, which will enter late-stage development in 2021.In November 2020, Biogen signed a collaboration with Sage Therapeutics SAGE, which added a late-stage program (zuranolone) in depression and movement disorders.
Time to Invest in Legal Marijuana
If you’re looking for big gains, there couldn’t be a better time to get in on a young industry primed to skyrocket from $17.7 billion back in 2019 to an expected $73.6 billion by 2027.
After a clean sweep of 6 election referendums in 5 states, pot is now legal in 36 states plus D.C. Federal legalization is expected soon and that could be a still greater bonanza for investors. Even before the latest wave of legalization, Zacks Investment Research has recommended pot stocks that have shot up as high as +285.9%
You’re invited to check out Zacks’ Marijuana Moneymakers: An Investor’s Guide. It features a timely Watch List of pot stocks and ETFs with exceptional growth potential.
Today, Download Marijuana Moneymakers FREE >>
Want the latest recommendations from Zacks Investment Research? Today, you can download 7 Best Stocks for the Next 30 Days. Click to get this free report
Biogen Inc. (BIIB) : Free Stock Analysis Report
Sangamo Therapeutics, Inc. (SGMO) : Free Stock Analysis Report
Sage Therapeutics, Inc. (SAGE) : Free Stock Analysis Report
Denali Therapeutics Inc. (DNLI) : Free Stock Analysis Report
To read this article on Zacks.com click here.