Lord Lloyd-Webber has signed up as a volunteer for the Oxford Covid-19 vaccine trial to expedite the reopening of theatres.
The composer said he will receive a dose of the experimental drug on Thursday as part of his crusade for live performances to resume.
"I am excited that tomorrow I am going to be vaccinated for the Oxford Covid-19 trial" he tweeted last night.
"I'll do anything to prove that theatres can reopen safely - ALW."
Lord Lloyd-Webber has been an outspoken critic of the Government's closure of live music venues during the lockdown, and its response to the arts industry.
He has spent £150,000 on safety measures at his six theatres.
Phase I of the Oxford vaccine involving 500 volunteers for human trials showed that it generates an immune response against the disease.
The trial is currently in a combined phase I and III stage with participants in the UK, South Africa and Brazil.
As a volunteer, Lord Lloyd-Webber will either receive the vaccine created by Oxford scientists or a placebo.